Uterine pathology of women with antenatally diagnosed placenta accreta spectrum (PAS) disorders
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Abstract
To determine the rate of women with antenatally diagnosed placenta accreta spectrum (PAS) who are pathologically unconfirmed and associated factors. This study was conducted in the Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Thailand. Medical records of women with an antenatal diagnosis of PAS who underwent hysterectomy between January 2015 and July 2022 were reviewed. Records of 50 women were reviewed. All women had placenta previa, and most (94.0%) had a prior history of cesarean delivery. Four women were found to have no PAS on pathological examination, accounting for a false-positive rate of 8.0% (95% confidence interval 2.20%-19.2%). Coexisting adenomyosis was more likely to be noted among women without PAS on pathologic examination than among those with pathologically confirmed PAS (50.0% versus 17.8%, respectively). Among women with clinically suspected extensive myometrial involvement, grade 3 PAS was pathologically diagnosed in only 57.1% with coexisting adenomyosis, that was lower than that in women without adenomyosis (84.6%). The false-positive rate of prenatal PAS diagnosis in this study was 8.0%. Coexisting adenomyosis appeared to affect the accuracy of the antenatal diagnosis of PAS.
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