Immediate effects of low-frequency repetitive transcranial magnetic stimulation to augment task-specific training in sub-acute stroke
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Published:
Mar 1, 2015
Keywords:
Non-invasive Brain stimulation Neural plasticity Task-specific training Stroke
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Abstract
The current study examined the immediate effects of a single-session low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) with task-specific training in sub-acute stroke. Sixteen participants were randomly received either active LF-rTMS (experimental group) over the non-lesioned hemisphere or sham stimulation (control group). Consequently, both groups underwent task-specific training with the paretic hand and constrained the non-paretic hand by a mitt for 1 hour. The authors evaluated the corticospinal excitability of the non-lesioned hemisphere (evaluated by motor evoked potential (MEP) amplitude) and the behavioral outcomes of both hands (evaluated by total movement time (TMT) of the Wolf Motor Function Test). There were significant differences between the two groups in the MEP amplitude of the non-lesioned hemisphere at post LF-rTMS and post motor training. Comparing to that of the baseline, the experimental group showed a greater decrease in TMT of the paretic hand immediately after active LF-rTMS than the control group. Additionally, the TMT of experimental group further decreased after the motor training and it was significantly less than that of the control group. Therefore, the task-specific training effect was augmented by LF-rTMS to improve the performance of paretic hand in sub-acute stroke.
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How to Cite
Thanakamchokchai, J., Tretriluxana, J., Jalayondeja, C., & Pakaprot, N. (2015). Immediate effects of low-frequency repetitive transcranial magnetic stimulation to augment task-specific training in sub-acute stroke. Asia-Pacific Journal of Science and Technology, 20(1), 105–119. https://doi.org/10.14456/kkurj.2015.10
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Research Articles
References
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[17] Takeuchi N, Toshima M, Chuma T, Matsuo Y, Ikoma K. Repetitive Transcranial Magnetic Stimulation of the Unaffected Hemisphere in a Patient Who Was Forced to Use the Affected Hand. Am J Phys Med Rehabil. 2008;87[1] :74-7.
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[19] Williams JA, Pascual-Leone A, Fregni F. Interhemispheric Modulation Induced by Cortical Stimulation and Motor Training. Am Phys Ther Assoc. 2010;90:398-410.
[20] Kleim JA, Jones TA. Principles of Experience-Dependent Neural Plasticity: Implications for Rehabilitation After Brain Damage. J Speech Lang Hear Res. February 2008;51:S225-S39.
[21] Winstein CJ, Wolf S. L. Stroke Recovery and Rehabilitation. Stein J, Harvey Richard L, Macko Richard F, Winstein Caloree J, Zorowitz Richard D, editor. New York: Demos Medical Publishing 2009.
[22] Dobkin BH. Strategies for stroke rehabilitation. Neurology.2004;3:528-36.
[23] Liepert J. Motor Cortex Excitability in Stroke Before and After Constraint-induced Movement Therapy. Cog Behav Neurol. 1, March 2006;19:41-7.
[24] Tretriluxana J, Runnarong N, Tretriluxana S,Prayoonwiwat N, Vachalathiti R, Winstein C. Feasibility Investigation of the Accelerated Skill Acquisition Program [ASAP] : Insights into Reach-to-Grasp Coordination of Individuals with Postacute Stroke Top Stroke Rehabil. 2013;20[2] :151-60.
[25] Wolf SL, Catlin PA, Ellis M, Archer AL, Morgan B ,and Piacentino A. Assessing Wolf Motor Function Test as Outcome Measure for Research in Patients After Stroke. Stroke 2001;32:1635-9.
[26] Maeda F, Pascual-Leone A. Transcranial magnetic stimulation: studying motor neurophysiology of psychiatric disorders. J Psychopharmacol. 2003;168:359-76.
[27] Hallett M, Chokroverty S. Magnetic stimulation in clinical neyrophysiology. 2nd ed. United States of America 2005.
[28] Fregni F, Boggio PS, Valle AC, Rocha RR, Duarte J, Ferreira M.J.L. et al. A Sham-Controlled Trial of a 5-Day Course of Repetitive Transcranial Magnetic Stimulation of the Unaffected Hemisphere in Stroke Patients. Stroke.2006;37:2115-22.
[29] Nowak DA, Grefkes C, Dafotakis M, Eickhoff S, Kust J, Karbe H. et al. Effects of Low-Frequency Repetitive Transcranial Magnetic Stimulation of the Contralesional Primary Motor Cortex on Movement Kinematics and Neural Activity in Subcortical Stroke. Arch Neurol.2008;65[6] :741-7.
[30] Tretriluxana J, Kantak S, Tretrilux-ana S, Wu Allan D, & Fisher Beth E. Low frequency repetitive transcranial magnetic stimulation to the non-lesioned hemisphere improves paretic arm reach-to-grasp performance after chronic stroke. Disabil Rehabil Assist Technol. 2013;8[2] :121-4.
[31] Ziemann U. TMS Induced Plasticity in Human CortexRev Neurosci 2004;15:253-66.
[32] Thickbroom GW. Transcranial magnetic [stimulation and synaptic plasticity: experimental framework and human models. Exp Brain Res. 2007;180:583-93.
[33] Perkins David N, Salomon Gavriel. TRANSFER OF LEARNING. International Encyclopedia of Education September 2 1992 [updated Sep 1, 2014]. 2nd:[Available from: https://learnweb.harvard.edu/alps/thinking/docs/traencyn.htm.
[34] Higgins J, Koski L, and Xie H. Combining rTMS and Task-Oriented Training in the Rehabilitation of the Arm after Stroke: A Pilot Randomized Controlled Trial. Stroke Res Treat. 2013;Article ID 539146:1-8.
[2] impact of stroke [Stroke statistics] [updated [updated Tue, 9 Sep 2014 21:36:00 PM].]. Available from: Available from: http://www.stroke-association.org/STROKEORG/AboutStroke/Impact-of-Stroke_UCM_310728_Article.jsp#main-Content.
[3] Bureau of Non Communicable Disease. The prevalence of in-patients with cerebral vascular disease [updated Thu,4 Sep 2014 14:11:00 PM.]. Available from: http://thaincd.com/information-statistic/non-communicable-disease-data.php.
[4] Desrosiers J, Malouin F, Richards C, Bourbonnais D, Rochette A, Bravo G. Comparison of changes in upper and lower extremity impairments and disabilities after stroke. Int J Rehabil Res.2003;26[2] :109-16.
[5] Thrasher TA, Zivanovic V, McIlroy W, Popovic MR Rehabilitation of Reaching and Grasping Function in Severe Hemiplegic Patients Using Functional Electrical Stimulation Therapy. Neurorehabil Neural Repair. 2008;22[6] :706-14.
[6] Pelton T, van Vliet P, Hollands K. Interventions for improving coordination of reach to grasp following stroke: a systematic review Int J Evid Based Healthc. 2012;10[2] :89-102.
[7] Kwakkel G, Kollen BJ, van der Grond J, and Prevo AJ. Probability of Regaining Dexterity in the Flaccid Upper Limb: Impact of Severity of Paresis and Time Since Onset in Acute Stroke. Stroke. 2003;34[9] :2181-6.
[8] Lang CE, Wagner JM, Edwards DF, Sahrmann SA, Dromerick AW. Recovery of Grasp versus Reach in People with Hemiparesis Poststroke. Neurorehabil Neural Repair. 2006;20[4] :444-54.
[9] Harris-Love ML, Cohen LG. Non-invasive Cortical Stimulation in Neurorehabilitation: A Review. Arch Phys Med Rehabil. 2006;87[12, Supplement 1] :84-93.
[10] Rossini PM, Rossi S Transcranial magnetic stimulation Diagnostic, therapeutic, and research potential. Neurology. 2007;68:484-8.
[11] Fregni F, Pascual-Leone A. Hand Motor Recovery After Stroke: Tuning the Orchestra to Improve Hand Motor Function. Cogn Behav Neurol 2006;19[1] :21-33.
[12] Shimizu T, Hosaki A, Hino T, Sato M, Komori T, Hirai S. et al. . Motor cortical disinhibition in the unaffected hemisphere after unilateral cortical stroke. Brain. 2002;125:1896-907.
[13] Cathrin M. Bütefisch MW, Johannes Netz, Rüdiger J. Seitz and Volker Hömberg. Relationship Between Interhemispheric Inhibition and Motor Cortex Excitability in Subacute Stroke Patients. Neurorehabil Neural Repair. 2008;22:4-21.
[14] Takeuchi N, Chuma T, Matsuo Y, Watanabe I, Ikoma K. Repetitive Transcranial Magnetic Stimulation of Contralesional Primary Motor Cortex Improves Hand Function After Stroke. Stroke.2005;36[12] :2681-6.
[15] Dafotakis M, Grefkes C, Wang L, Fink G, Nowak D. The effects of 1 Hz rTMS over the hand area of M1 on movement kinematics of the ipsilateral hand. J Neural Transm. 2008;115[9] :1269-74.
[16] Takeuchi N, Tada T, Toshima M, Chuma T, Matsuo Y, and Ikoma K. Inhibition of the unaffected motor cortex by 1 Hz. Repetitive Transcranial Magnetic Stimulation enhances motor performance and training effect of the paretic hand in patients with chronic stroke. J Rehabil Med. 2008;40:298-303.
[17] Takeuchi N, Toshima M, Chuma T, Matsuo Y, Ikoma K. Repetitive Transcranial Magnetic Stimulation of the Unaffected Hemisphere in a Patient Who Was Forced to Use the Affected Hand. Am J Phys Med Rehabil. 2008;87[1] :74-7.
[18] Vongvaivanichakul P, Tretriluxana J, Bovonsunthonchai S, Pakaprot N, Laksanakorn W. Reach-to-Grasp Training in Individuals with Chronic Stroke Augmented by Low-Frequency Repetitive Transcranial Magnetic Stimulation. J Med Assoc Thai 2014;97 [Suppl. 7] :S1-S5.
[19] Williams JA, Pascual-Leone A, Fregni F. Interhemispheric Modulation Induced by Cortical Stimulation and Motor Training. Am Phys Ther Assoc. 2010;90:398-410.
[20] Kleim JA, Jones TA. Principles of Experience-Dependent Neural Plasticity: Implications for Rehabilitation After Brain Damage. J Speech Lang Hear Res. February 2008;51:S225-S39.
[21] Winstein CJ, Wolf S. L. Stroke Recovery and Rehabilitation. Stein J, Harvey Richard L, Macko Richard F, Winstein Caloree J, Zorowitz Richard D, editor. New York: Demos Medical Publishing 2009.
[22] Dobkin BH. Strategies for stroke rehabilitation. Neurology.2004;3:528-36.
[23] Liepert J. Motor Cortex Excitability in Stroke Before and After Constraint-induced Movement Therapy. Cog Behav Neurol. 1, March 2006;19:41-7.
[24] Tretriluxana J, Runnarong N, Tretriluxana S,Prayoonwiwat N, Vachalathiti R, Winstein C. Feasibility Investigation of the Accelerated Skill Acquisition Program [ASAP] : Insights into Reach-to-Grasp Coordination of Individuals with Postacute Stroke Top Stroke Rehabil. 2013;20[2] :151-60.
[25] Wolf SL, Catlin PA, Ellis M, Archer AL, Morgan B ,and Piacentino A. Assessing Wolf Motor Function Test as Outcome Measure for Research in Patients After Stroke. Stroke 2001;32:1635-9.
[26] Maeda F, Pascual-Leone A. Transcranial magnetic stimulation: studying motor neurophysiology of psychiatric disorders. J Psychopharmacol. 2003;168:359-76.
[27] Hallett M, Chokroverty S. Magnetic stimulation in clinical neyrophysiology. 2nd ed. United States of America 2005.
[28] Fregni F, Boggio PS, Valle AC, Rocha RR, Duarte J, Ferreira M.J.L. et al. A Sham-Controlled Trial of a 5-Day Course of Repetitive Transcranial Magnetic Stimulation of the Unaffected Hemisphere in Stroke Patients. Stroke.2006;37:2115-22.
[29] Nowak DA, Grefkes C, Dafotakis M, Eickhoff S, Kust J, Karbe H. et al. Effects of Low-Frequency Repetitive Transcranial Magnetic Stimulation of the Contralesional Primary Motor Cortex on Movement Kinematics and Neural Activity in Subcortical Stroke. Arch Neurol.2008;65[6] :741-7.
[30] Tretriluxana J, Kantak S, Tretrilux-ana S, Wu Allan D, & Fisher Beth E. Low frequency repetitive transcranial magnetic stimulation to the non-lesioned hemisphere improves paretic arm reach-to-grasp performance after chronic stroke. Disabil Rehabil Assist Technol. 2013;8[2] :121-4.
[31] Ziemann U. TMS Induced Plasticity in Human CortexRev Neurosci 2004;15:253-66.
[32] Thickbroom GW. Transcranial magnetic [stimulation and synaptic plasticity: experimental framework and human models. Exp Brain Res. 2007;180:583-93.
[33] Perkins David N, Salomon Gavriel. TRANSFER OF LEARNING. International Encyclopedia of Education September 2 1992 [updated Sep 1, 2014]. 2nd:[Available from: https://learnweb.harvard.edu/alps/thinking/docs/traencyn.htm.
[34] Higgins J, Koski L, and Xie H. Combining rTMS and Task-Oriented Training in the Rehabilitation of the Arm after Stroke: A Pilot Randomized Controlled Trial. Stroke Res Treat. 2013;Article ID 539146:1-8.