Effect of corn meal and ganoderma lucidum P. karst infested corn meal on serum immunoglobulin and cholesterol in ICR mice(Thai)

Abstract

The objective of this experiment was to study the effect of corn meal (CM) and Ganoderma-infested
corn (GCM) meal on plasma immunoglobulin A (IgA), immunoglobulin G (IgG) and cholesterol in ICR mice.
Ten 7-week old males with the average weight of 30+ 0.68 g were selected using a complete randomized
design. The mice were separated randomly into two groups. The first group was fed ad libitum with CM and the
second group was fed ad libitum on CM: GCM at a mix ratio of 50:50. After 29 days, all mice were weighed
and analyzed for IgA, IgG and their spleens were checked. Feed intake on CM was significantly (p<0.05)
greater than that on GCM but the degree of digestibility of GCM by IRC mouse was significantly greater 


(p<0.01) than the CM digestibility. There was no significant difference in the weight of their hearts, lungs and
livers, but spleens of the CM fed mice were slightly larger than those of the GCM fed mice. Levels of
cholesterol and immunoglobulin in the blood plasma of the experimental mice were analyzed and the level of
cholesterol of the GCM fed mice was significantly lower (p<0.01) than that from the CM fed mice. There were
no significant differences (p>0.05) in the levels of immunoglobulins in the blood plasma of all mice. These
findings suggest the potential of using corn meal inoculated with Ganoderma for healthy feed in animals.