Oocysticidal Activity of Thai Medicinal Plant Extracts on Isospora suis and Eimeria tenella(Thai)

Abstract

Anti-coccidial activity of 50% methanolic extracts of Combretum quadrangulare seed, Annona sguamosa seed, and Streblus asper stem-bark on Isospora suis and Eimeria tenella, pathogenic coccidia of pig and poultry respectively, were evaluated. Oocysticidal effect was only found for Combretum quadrangulare seed extract (32 mg/ml) on Isospora suis, resulting in a significant reduction (p ≤ 0.001) in oocyst sporulation rate. However, Annona sguamosa seed and Streblus asper stem-bark extracts had no effect. In the case of Eimeria tenella, oocyst sporulation rate was not affected by any tested extracts. In conclusion, the seed extract of Combretum quadrangulare possesses oocysticidal activity and should be further studied as an oocysticide for Isospora suis.